The mission of the Pittsburgh NMR Center for Biomedical Research is to advance state-of-the-art in vivo magnetic resonance imaging (MRI) and spectroscopy (MRS) techniques to better understand tissue and organ function, and to make these tools available to the greater biomedical research community. Center investigators from Carnegie Mellon University and the University of Pittsburgh use animal and cellular models in their studies and have diverse multidisciplinary expertise.
The MRI equipment housed by the Pittsburgh NMR Center includes Bruker BioSpec 4.7T/40 cm and 7.0T/21 cm systems, as well as a Bruker AVANCE 11.7T/8.9 cm system for imaging fixed samples or mice and rats in vivo. The MRS capabilities of the Pittsburgh NMR Center include access to four high resolution Bruker AVANCE DRX NMR spectrometers, which have four RF channels and are routinely used for high resolution protein NMR spectroscopy and NMR spectroscopy of biological samples and metabolites. Additionally, the Center houses a Bruker MiniSpec 0.47T instrument for routine relaxation time measurements in tissue samples, cell suspensions, and contrast agents.